St. Manno Hypogeum is in the locality Ferro di Cavallo, at a short distance from Perugia. It is in a Mmedieval house, property of Knights of Malta. Hypogeum consists of a large rectangular room with a vaulted ceiling and is completely faced with a layer of travertine slabs, perfectly aligned and joined together “a secco”, without the use of mortar. On the longer sides, two small squared chambers open symmetrically, one to the left and one to the right of the room, and both have a vaulted ceiling. Above the arch of access in the left chamber, a three line long Etruscan inscription each of different length has been sculpted. The text mentions the tomb built by Aule and Larth from Precu family, and the father Larth and the mother, from Cestna family, are commemorated.